Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1127 | Neuroendocrinology | ICEECE2012

Regional distributions of kisspeptin and gonadotropin-inhibiting hormone peptides in ovine and rat brains

Hasegawa Y. , Hashimoto O. , Tsutsui K.

The reproductive system is controlled by (GnRH) secretion from the brain, which is finely modulated by a number of factors, including gonadal sex steroids and inhibins. It was recently claimed that kisspeptin (KP) and gonadotropin inhibitory hormone (GnIH) neurons are regulators of GnRH secretion. Therefore, we have developed highly specific and sensitive fluoro-immunoassays (FIAs) using Eu-labeled antigens for KP 10 and GnIH. In this study, the distributions of KP 10 and GnIH...

ea0029p69 | Adrenal cortex | ICEECE2012

New quick cortisol assay during adrenal vein sampling in patients with primary aldosteronism

Yoneda T. , Karashima S. , Demura M. , Oda N. , Mori S. , Kometani M. , Masashi O. , Hashimoto A. , Sawamura T. , Yamagishi M. , Takeda Y.

Background: Adrenal vein sampling (AVS) is the gold standard test for identification of unilateral primary aldosteronism (PA) which is curable by surgery, but is a difficult procedure with low success rates. Rapid cortisol assays during AVS improved AVS success rates.Methods: We have developed a gold nanoparticles based immunochromatographic quick cortisol assay (QCA) in which cortisol concentration could be measured both quantitatively and semi-quantita...